WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:
Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName #Gene EntrezGene Statistics
Metabolic pathways 64 349565 1355 56922 445 2687 1352 6389 2806 1431 7385 139596 1738 4249 6610 124454 25796 10229 48 2585 1743 8050 29926 50 7915 4830 23530 527 54480 284098 4719 4329 1962 4594 6391 26229 7086 353 506 8702 27430 622 1629 64087 4522 8803 126792 271 5096 25834 219 79623 2235 1594 36 51 9 283208 38 7372 498 5337 132 11112 8395 C=1130;O=64;E=13.73;R=4.66;rawP=1.76e-24;adjP=1.81e-22
Valine, leucine and isoleucine degradation 12 5096 36 4594 1962 4329 56922 38 219 1738 1629 64087 11112 C=44;O=12;E=0.53;R=22.45;rawP=1.35e-13;adjP=6.95e-12
Citrate cycle (TCA cycle) 8 8803 50 6391 48 1431 1738 1743 6389 C=30;O=8;E=0.36;R=21.95;rawP=2.08e-09;adjP=7.14e-08
Glyoxylate and dicarboxylate metabolism 6 38 5096 50 4594 48 1431 C=18;O=6;E=0.22;R=27.43;rawP=5.13e-08;adjP=1.32e-06
Propanoate metabolism 7 38 8803 5096 219 4594 1962 4329 C=32;O=7;E=0.39;R=18.00;rawP=9.72e-08;adjP=2.00e-06
Ubiquitin mediated proteolysis 11 8916 5071 8451 8651 90293 8453 5371 25898 23327 672 22954 C=135;O=11;E=1.64;R=6.71;rawP=8.86e-07;adjP=1.44e-05
Lysine degradation 7 38 219 83852 1962 5352 1743 55217 C=44;O=7;E=0.53;R=13.09;rawP=9.76e-07;adjP=1.44e-05
Peroxisome 8 390916 5194 225 1962 51 10478 5189 8528 C=79;O=8;E=0.96;R=8.33;rawP=5.52e-06;adjP=7.11e-05
Fatty acid metabolism 6 38 36 219 1962 51 126129 C=43;O=6;E=0.52;R=11.48;rawP=1.30e-05;adjP=0.0001
Oxidative phosphorylation 9 1355 4719 6391 7385 527 506 498 1352 6389 C=132;O=9;E=1.60;R=5.61;rawP=3.65e-05;adjP=0.0004


WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).